Press Release from Umeå University

Swedish researchers map the risks of new virus epidemic in Europe

[2014-04-07] The risk of dengue fever beginning to spread in Europe is imminent. According to researchers from Umeå University, this is no longer just an issue for the scientific community but also for politicians and policy makers, who need to be prepared and develop preventive measures.

With a changing climate and rising temperatures in Europe, the incidence of the Aedes aegypti mosquito has also increased. The mosquito is the main vector of dengue that can cause haemorrhagic fever. Although no outbreak of the disease has not yet occurred in Europe, researchers at the Epidemiology and Global Health unit at Umeå University claim that there is now good living conditions for the mosquito in Europe and that it is therefore only a matter of time before we see an epidemic here. The Aedes albopictus mosquito has already established itself in large parts of Europe. Even though it is not as competent a vector as Aedes aegypti, several domestic cases of the disease have been observed in countries such as France and Croatia.

“The last outbreak of dengue in Portuguese Madeira when several thousand became ill, shows that it is no longer a theoretical possibility that the disease can take hold in Europe. It is a reality that can strike at any time,” says Raman Preet, researcher and scientific project manager of the Dengue Tools project at the Department of Epidemiology and Global Health, Umeå University.  “When the disease shows up in Europe it has probably accompanied travellers in areas in the world where the disease is established. Then it will be spread with the help of the Aedes mosquito”.

The risk for Swedish travellers to be infected by dengue is highest when going to Sri Lanka and Bangladesh, while most cases in Sweden stems from trips to Thailand. There is currently no vaccine that can protect against dengue, nor is there any treatment when the illness strikes. Symptoms are similar to those of severe cold with fever, headache, muscle and joint pain, or upset stomach. The disease can be life threatening when it affects children, the elderly and chronically ill. In severe cases it can develop into a haemorrhagic fever.

The previous models used to study the spread of dengue and especially the living conditions for the Aedes mosquito has taken up the average temperature in different areas. Jing Helmersson, PhD student within the EU-funded DT project at Umeå University, demonstrates in her studies that it is not enough. These calculations must also include the diurnal temperature distribution in different areas, and temporal trends when assessing the potential for an epidemic caused by dengue. Therefore, Jing Helmersson has developed a climate model with historical data from 1901 to the present day, whose projections extends to 2099. The results show a strong link between climate change and increased ability for mosquitos to spread the disease in Europe.

“In our analyses, we can see that climate change, including the extreme weather with large daily temperature fluctuations in different areas of Europe, causes a large relative increase in the potential for epidemic spread of dengue fever,” says Jing Helmersson. “It mainly concerns areas in southern and central Europe where the potential for proliferation previously has been small. At the same time we see that the spread potential will decrease in warm areas of the world, because the temperatures get too high.”

Following the results of the research project, Jing Helmersson believes that it is important to continue with the mapping of future risks of dengue infection, especially in temperate regions of the Northern Hemisphere. Increased globalization and the influx of viruses carried by flight passengers further heightens the risks.

“Perhaps the most important of these studies is that they give us a better understanding of the risks of a future epidemic of dengue fever,” says Jing Helmersson. “This type of modelling where we use weather and climate data makes it possible to forewarn the authorities in countries that are at risk of dengue epidemics, so that they in turn can prepare and start to act.”

For more information on the studies on climate models, please contact:
Jing Helmersson
Phone: +46 90 785 29 35

For more information about the research Dengue Tools, contact:
Raman Preet
Phone: +46 72 706 13 65

Facts, DengueTools

The DengueTools project is funded by the European Commission for four years and led by Annelies Wilder Smith, an expert on dengue fever  and Visiting Professor at the Epidemiology and Global Health unit at Umeå University. The project aims to expand knowledge on dengue and to develop tools for monitoring and control of the disease.

The project is run by a consortium of 14 member organizations from around the world, which in turn are divided into 12 Work Packages and 3 research areas.

• Research area 1 focuses on developing new tools for the surveillance of dengue fever.

• Research area 2 carries out laboratory and community based studies to develop new tools for the prevention of dengue fever in children.

• Research area 3 examines the risk of the global spread of dengue fever.

Joacim Rocklöv, Associate Professor at the Department of Epidemiology and Global Health, Umeå University, leads Research area 3, as well as Work Package 8, in which also Mikkel Quam, project assistant and aspiring graduate student, is active.

Peter Byass, Professor and Director of the Umeå Centre for Global Health, leads Work Package 9.

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Editor: Mattias Grundström Mitz

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